Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate, process of its preparation, medicaments in which this substance is comprised, use of this compound and 2-chloro-3-cyanobenzaldehyde as intermediate employed during preparation of this compound

In the present invention there are disclosed rac-isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)-1,4-dihydro -2,6-dimethylpyridine-3,5-dicarboxylate of the general formula I and pure enantiomers thereof, further processes of their preparation and their use as medicaments intended particularly...

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Hauptverfasser: SCHUURMAN TEUNIS DR, SCHOHE-LOOP RUDOLF DR, GAO ZHAN DR, SCHMIDT BERNARD DR, DE JONGE MAARTEN, MEIER HEINRICH DR, HARTWIG WOLFGANG DR, JUNGE BODO DR
Format: Patent
Sprache:cze ; eng
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Zusammenfassung:In the present invention there are disclosed rac-isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)-1,4-dihydro -2,6-dimethylpyridine-3,5-dicarboxylate of the general formula I and pure enantiomers thereof, further processes of their preparation and their use as medicaments intended particularly for treating cerebral and neuronal diseases, as well as an intermediate for preparing the above indicated compound. Řešení se týká rac-izopropyl-(2-methoxyethyl)-4-(2-chlor-3-kyano-fenyl)-1,4-dihydro-2,6-dimethylpyridin-3,5-dikarboxylátu vzorce I a jeho čistých enantiomerů, způsobu jejich výroby a jejich použití jako léčiv, obzvláště pro ošetření cerebrálních a neuronálních onemocnění a meziproduktu pro výrobu této sloučeniny.ŕ