OXAZOLIDINONE DERIVATIVES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATION BASED THEREON
Sloučeniny obecného vzorce I, kde X je O, S, NH; Y je aziridinový, azetidinový, pyrrolidinový, piperidinový, 1-oxa-azaspiro/4,5/dekan-8-ylový, hexahydroazepinový nebo 4-R.sup.4.n.-piperazinový zbytek, který je popřípadě jednou substituován skupinou R.sup.2.n., a který je popřípadě navíc substituován...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | cze ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | GANTE JOACHIM MELZER QUIDO DR PRUCHER HELMUT DR BERNOTAT-DANIELOWSKI SABINE DR WURZIGER HANNS DR RADDATZ PETER DR JURACZYK HORST DR |
| description | Sloučeniny obecného vzorce I, kde X je O, S, NH; Y je aziridinový, azetidinový, pyrrolidinový, piperidinový, 1-oxa-azaspiro/4,5/dekan-8-ylový, hexahydroazepinový nebo 4-R.sup.4.n.-piperazinový zbytek, který je popřípadě jednou substituován skupinou R.sup.2.n., a který je popřípadě navíc substituován skupinou OZ, SZ nebo N(Z).sub.2.n. a/nebo karbonylovým kyslíkem; Z je vždy H, A, fenyl-C.sub.k.n.H.sub.2k.n. nebo Ac; R.sub.1.n. je fenylový zbytek monosubstituovaný zbytkem zvoleným ze skupiny zahrnující CN, H.sub.2.n.N-CH.sub.2.n.-, (A).sub.2.n.N-CH.sub.2.n.-, H.sub.2.n.N-C(=NH)-, H.sub.2.n.N-C(=NH)-NH-, H.sub.2.n.N-C(=NH)-NH-CH.sub.2.n.-, HO-NH-C(=NH)- nebo HO-NH-C(=NH)-NH-; R.sup.2.n. je -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n. nebo -C.sub.n.n.H.sub.2n.n.--O-C.sub.p.n.H.sub.2p.n.-COOR.sup.3.n., R.sup.3.n. je H, A nebo benzyl; R.sup.4.n. je H, A, benzyl nebo -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n.; A je vždy alkyl s 1 až 6 atomy uhlíku; Ac je acyl s 1 až 11 atomy uhlíku; k a m znamená číslo 0, ŕ
Novel compounds of the formula I in which R , X and Y have the meanings given in Patent Claim 1, and their salts inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for the treatment of thromboses, apoplexy, cardiac infarcts, inflammations, arteriosclerosis, osteoporosis and tumours. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CZ285761B6</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CZ285761B6</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CZ285761B63</originalsourceid><addsrcrecordid>eNqFyrEKwjAUheEsDqI-g_cB6qBidb1Nbmmg5oYkLdKlFImT2EJ9f6zQwc3pwH--pej5hg2XWmnDhkCR0zUGXZNPwDqW5D1wDqEg7aZAFt10s0nmVHkCNApsge6KkqqgJZa_EjL0pL7cEZu1WDy65xg3867ENqcgi10c-jaOQ3ePr_huZXO4nM7pPkuP_8UH-hE3IA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>OXAZOLIDINONE DERIVATIVES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATION BASED THEREON</title><source>esp@cenet</source><creator>GANTE JOACHIM ; MELZER QUIDO DR ; PRUCHER HELMUT DR ; BERNOTAT-DANIELOWSKI SABINE DR ; WURZIGER HANNS DR ; RADDATZ PETER DR ; JURACZYK HORST DR</creator><creatorcontrib>GANTE JOACHIM ; MELZER QUIDO DR ; PRUCHER HELMUT DR ; BERNOTAT-DANIELOWSKI SABINE DR ; WURZIGER HANNS DR ; RADDATZ PETER DR ; JURACZYK HORST DR</creatorcontrib><description>Sloučeniny obecného vzorce I, kde X je O, S, NH; Y je aziridinový, azetidinový, pyrrolidinový, piperidinový, 1-oxa-azaspiro/4,5/dekan-8-ylový, hexahydroazepinový nebo 4-R.sup.4.n.-piperazinový zbytek, který je popřípadě jednou substituován skupinou R.sup.2.n., a který je popřípadě navíc substituován skupinou OZ, SZ nebo N(Z).sub.2.n. a/nebo karbonylovým kyslíkem; Z je vždy H, A, fenyl-C.sub.k.n.H.sub.2k.n. nebo Ac; R.sub.1.n. je fenylový zbytek monosubstituovaný zbytkem zvoleným ze skupiny zahrnující CN, H.sub.2.n.N-CH.sub.2.n.-, (A).sub.2.n.N-CH.sub.2.n.-, H.sub.2.n.N-C(=NH)-, H.sub.2.n.N-C(=NH)-NH-, H.sub.2.n.N-C(=NH)-NH-CH.sub.2.n.-, HO-NH-C(=NH)- nebo HO-NH-C(=NH)-NH-; R.sup.2.n. je -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n. nebo -C.sub.n.n.H.sub.2n.n.--O-C.sub.p.n.H.sub.2p.n.-COOR.sup.3.n., R.sup.3.n. je H, A nebo benzyl; R.sup.4.n. je H, A, benzyl nebo -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n.; A je vždy alkyl s 1 až 6 atomy uhlíku; Ac je acyl s 1 až 11 atomy uhlíku; k a m znamená číslo 0, ŕ
Novel compounds of the formula I in which R , X and Y have the meanings given in Patent Claim 1, and their salts inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for the treatment of thromboses, apoplexy, cardiac infarcts, inflammations, arteriosclerosis, osteoporosis and tumours.</description><edition>6</edition><language>cze ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19991117&DB=EPODOC&CC=CZ&NR=285761B6$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19991117&DB=EPODOC&CC=CZ&NR=285761B6$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GANTE JOACHIM</creatorcontrib><creatorcontrib>MELZER QUIDO DR</creatorcontrib><creatorcontrib>PRUCHER HELMUT DR</creatorcontrib><creatorcontrib>BERNOTAT-DANIELOWSKI SABINE DR</creatorcontrib><creatorcontrib>WURZIGER HANNS DR</creatorcontrib><creatorcontrib>RADDATZ PETER DR</creatorcontrib><creatorcontrib>JURACZYK HORST DR</creatorcontrib><title>OXAZOLIDINONE DERIVATIVES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATION BASED THEREON</title><description>Sloučeniny obecného vzorce I, kde X je O, S, NH; Y je aziridinový, azetidinový, pyrrolidinový, piperidinový, 1-oxa-azaspiro/4,5/dekan-8-ylový, hexahydroazepinový nebo 4-R.sup.4.n.-piperazinový zbytek, který je popřípadě jednou substituován skupinou R.sup.2.n., a který je popřípadě navíc substituován skupinou OZ, SZ nebo N(Z).sub.2.n. a/nebo karbonylovým kyslíkem; Z je vždy H, A, fenyl-C.sub.k.n.H.sub.2k.n. nebo Ac; R.sub.1.n. je fenylový zbytek monosubstituovaný zbytkem zvoleným ze skupiny zahrnující CN, H.sub.2.n.N-CH.sub.2.n.-, (A).sub.2.n.N-CH.sub.2.n.-, H.sub.2.n.N-C(=NH)-, H.sub.2.n.N-C(=NH)-NH-, H.sub.2.n.N-C(=NH)-NH-CH.sub.2.n.-, HO-NH-C(=NH)- nebo HO-NH-C(=NH)-NH-; R.sup.2.n. je -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n. nebo -C.sub.n.n.H.sub.2n.n.--O-C.sub.p.n.H.sub.2p.n.-COOR.sup.3.n., R.sup.3.n. je H, A nebo benzyl; R.sup.4.n. je H, A, benzyl nebo -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n.; A je vždy alkyl s 1 až 6 atomy uhlíku; Ac je acyl s 1 až 11 atomy uhlíku; k a m znamená číslo 0, ŕ
Novel compounds of the formula I in which R , X and Y have the meanings given in Patent Claim 1, and their salts inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for the treatment of thromboses, apoplexy, cardiac infarcts, inflammations, arteriosclerosis, osteoporosis and tumours.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyrEKwjAUheEsDqI-g_cB6qBidb1Nbmmg5oYkLdKlFImT2EJ9f6zQwc3pwH--pej5hg2XWmnDhkCR0zUGXZNPwDqW5D1wDqEg7aZAFt10s0nmVHkCNApsge6KkqqgJZa_EjL0pL7cEZu1WDy65xg3867ENqcgi10c-jaOQ3ePr_huZXO4nM7pPkuP_8UH-hE3IA</recordid><startdate>19991117</startdate><enddate>19991117</enddate><creator>GANTE JOACHIM</creator><creator>MELZER QUIDO DR</creator><creator>PRUCHER HELMUT DR</creator><creator>BERNOTAT-DANIELOWSKI SABINE DR</creator><creator>WURZIGER HANNS DR</creator><creator>RADDATZ PETER DR</creator><creator>JURACZYK HORST DR</creator><scope>EVB</scope></search><sort><creationdate>19991117</creationdate><title>OXAZOLIDINONE DERIVATIVES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATION BASED THEREON</title><author>GANTE JOACHIM ; MELZER QUIDO DR ; PRUCHER HELMUT DR ; BERNOTAT-DANIELOWSKI SABINE DR ; WURZIGER HANNS DR ; RADDATZ PETER DR ; JURACZYK HORST DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CZ285761B63</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>cze ; eng</language><creationdate>1999</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GANTE JOACHIM</creatorcontrib><creatorcontrib>MELZER QUIDO DR</creatorcontrib><creatorcontrib>PRUCHER HELMUT DR</creatorcontrib><creatorcontrib>BERNOTAT-DANIELOWSKI SABINE DR</creatorcontrib><creatorcontrib>WURZIGER HANNS DR</creatorcontrib><creatorcontrib>RADDATZ PETER DR</creatorcontrib><creatorcontrib>JURACZYK HORST DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GANTE JOACHIM</au><au>MELZER QUIDO DR</au><au>PRUCHER HELMUT DR</au><au>BERNOTAT-DANIELOWSKI SABINE DR</au><au>WURZIGER HANNS DR</au><au>RADDATZ PETER DR</au><au>JURACZYK HORST DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>OXAZOLIDINONE DERIVATIVES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATION BASED THEREON</title><date>1999-11-17</date><risdate>1999</risdate><abstract>Sloučeniny obecného vzorce I, kde X je O, S, NH; Y je aziridinový, azetidinový, pyrrolidinový, piperidinový, 1-oxa-azaspiro/4,5/dekan-8-ylový, hexahydroazepinový nebo 4-R.sup.4.n.-piperazinový zbytek, který je popřípadě jednou substituován skupinou R.sup.2.n., a který je popřípadě navíc substituován skupinou OZ, SZ nebo N(Z).sub.2.n. a/nebo karbonylovým kyslíkem; Z je vždy H, A, fenyl-C.sub.k.n.H.sub.2k.n. nebo Ac; R.sub.1.n. je fenylový zbytek monosubstituovaný zbytkem zvoleným ze skupiny zahrnující CN, H.sub.2.n.N-CH.sub.2.n.-, (A).sub.2.n.N-CH.sub.2.n.-, H.sub.2.n.N-C(=NH)-, H.sub.2.n.N-C(=NH)-NH-, H.sub.2.n.N-C(=NH)-NH-CH.sub.2.n.-, HO-NH-C(=NH)- nebo HO-NH-C(=NH)-NH-; R.sup.2.n. je -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n. nebo -C.sub.n.n.H.sub.2n.n.--O-C.sub.p.n.H.sub.2p.n.-COOR.sup.3.n., R.sup.3.n. je H, A nebo benzyl; R.sup.4.n. je H, A, benzyl nebo -C.sub.m.n.H.sub.2m.n.-COOR.sup.3.n.; A je vždy alkyl s 1 až 6 atomy uhlíku; Ac je acyl s 1 až 11 atomy uhlíku; k a m znamená číslo 0, ŕ
Novel compounds of the formula I in which R , X and Y have the meanings given in Patent Claim 1, and their salts inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for the treatment of thromboses, apoplexy, cardiac infarcts, inflammations, arteriosclerosis, osteoporosis and tumours.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | cze ; eng |
| recordid | cdi_epo_espacenet_CZ285761B6 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | OXAZOLIDINONE DERIVATIVES, PROCESS OF THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATION BASED THEREON |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T22%3A26%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GANTE%20JOACHIM&rft.date=1999-11-17&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECZ285761B6%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |