DERIVATIVE IN POSITION OF 8-SUBSTITUTED 2-AMINOTETRALIN, PROCESSES OF ITS PREPARATION, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND ITS USE

DERIVATIVE IN POSITION OF 8-SUBSTITUTED 2-AMINOTETRALIN, PROCESSES OF ITS PREPARATION, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND ITS USE

A compound of the formula Z is hydrogen or halogen, Q is COR or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R is C1-C6 alkyl or an aromatic ring which may contain heteroatom...

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Hauptverfasser: BACKLUND HOOK BERIT CHRISTINA ELISABET, HACKSELL ULI ALF, ANDEN NILS-ENRIK, MELLIN EVA CHARLOTTA, YU HONG, BJORK ANNA LENA MARIA, HILLVER SVEN-ERIK, LIU YE, PERSSON EVA MARIE, VALLGARDA KARL JERK
Format: Patent
Sprache:cze ; eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A compound of the formula Z is hydrogen or halogen, Q is COR or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R is hydrogen or C1-C6 alkyl and R may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.