PROCESS FOR PREPARING ANTI-HAPTEN ANTIBODIES EXHIBITING HIGH AFFINITY AND PREPARATION FOR HAPTENS DETERMINATION

The invention relates to a method for the preparation of high-affinity anti-hapten antibodies and to a composition for the determination of haptens with the aid of these antibodies. The method for the preparation of these high-affinity anti-hapten antibodies is characterised in that, in a first stag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	STENZEL ROSWITH DR, LINXWEILER WINFRIED DR, WURZBURG UWE DR, SCHONEFELD ULRICH DR, RECKMANN BERND DR, HEUBNER ARNULF DR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	The invention relates to a method for the preparation of high-affinity anti-hapten antibodies and to a composition for the determination of haptens with the aid of these antibodies. The method for the preparation of these high-affinity anti-hapten antibodies is characterised in that, in a first stage, an animal is immunised several times with a hapten-protein conjugate and, in the second stage, the animal is immunised several times with a mixture of up to 3 hapten-protein conjugates, where the conjugates contain the same hapten but different proteins.