BRADYKININ ANTAGONISTS

A bradykinin antagonist of the formula: X(BKA)n wherein BKA is the peptide chain of a bradykinin antagonist peptide, X is a linking group and n is a whole number greater than 1. The BKA substituents may be the same or different. Monomeric antagonists of the formula X(BKA) are also disclosed. Also di...

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Bibliographische Detailangaben
Hauptverfasser:	CHERONIS JOHN C, WHALLEY ERIC T, ALLEN LISA GAY, BLODGETT JAMES K, EUBANKS SHADRACH R, NGUYEN KHE THANH
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A bradykinin antagonist of the formula: X(BKA)n wherein BKA is the peptide chain of a bradykinin antagonist peptide, X is a linking group and n is a whole number greater than 1. The BKA substituents may be the same or different. Monomeric antagonists of the formula X(BKA) are also disclosed. Also disclosed are bradykinin antagonists of the formula: (Y)(X)(BKA) where X and BKA have the meanings indicated above and Y is the peptide chain of an antagonist or agonist for a non-bradykinin receptor.