Reactive polymers and copolymers based on N-(2-hydroxypropyl)methacrylic amide, process of their preparation and their use for polymer medicament syntheses, further for modification of biologically active proteins and for preparation of gene transporting systems

The solution concerns reactive polymers and copolymers based on N-(2-hydroxypropyl)methacrylamide, which contain reactive thiazolidine-2-thione groups in side chains of the polymers or at the ends of polymer chains. The solution also includes a method of their preparation and their use for synthesis...

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Hauptverfasser: RIHOVA BLANKA RNDRSC, SUBR VLADIMIR CSC, ULBRICH KAREL DOC. DRSC
Format: Patent
Sprache:cze ; eng
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Zusammenfassung:The solution concerns reactive polymers and copolymers based on N-(2-hydroxypropyl)methacrylamide, which contain reactive thiazolidine-2-thione groups in side chains of the polymers or at the ends of polymer chains. The solution also includes a method of their preparation and their use for synthesis of polymer drugs and conjugates with proteins and preparation of gene delivery systems.