Preparations and methods relating to L-nucleosides, L-nucleotides, and their analog

Nucleoside and nucleotide compounds and their analogs/prodrugs are provided. Particularly contemplated compounds include 1- beta -L-ribofuranosyl-1,2,4-triazole-3-carboxamide, which may be modified and/or phosphorylated. Contemplated compounds may further be combined with other pharmacological compo...

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Hauptverfasser: ZEYTIN FUSUN N, LAU JOHNSON, RAMASAMY KANDA, RAKIC LJUBISA, HONG ZHI, TAM ROBERT, LIN CHINUNG
Format: Patent
Sprache:cze ; eng
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Zusammenfassung:Nucleoside and nucleotide compounds and their analogs/prodrugs are provided. Particularly contemplated compounds include 1- beta -L-ribofuranosyl-1,2,4-triazole-3-carboxamide, which may be modified and/or phosphorylated. Contemplated compounds may further be combined with other pharmacological compounds, especially including Ribavirin, antibodies, and cytokines. Preferred uses of contemplated compounds include use as an antiviral compound, anti-inflammatory compound, antineoplastic compound, and as a compound to stimulate cellular growth.