Water soluble rapamycin esters

A compound of the structure wherein R and R are each, independently, hydrogen or -COCH2-S-CH2CH2-O-CH2-(CH2OCH2)n-CH2-O-CH2CH2-OCH3; and n = 8 - 450; with the proviso that R and R are not both hydrogen, which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and ant...

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Bibliographische Detailangaben
Hauptverfasser:	LEE HYUK-KOO, ZHU TIANMIN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	A compound of the structure wherein R and R are each, independently, hydrogen or -COCH2-S-CH2CH2-O-CH2-(CH2OCH2)n-CH2-O-CH2CH2-OCH3; and n = 8 - 450; with the proviso that R and R are not both hydrogen, which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent.