Direct esterification of mycophenolic acid

Mycophenolate mofetil is made non-catalytically by refluxing mycophenolic acid with 2-morpholinoethanol in an inert organic solvent capable of azeotropic removal of water.

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Bibliographische Detailangaben
Hauptverfasser: DONEGAN GREGORY, SMITH, DENNIS, A, KNOX MARTIN
Format: Patent
Sprache:eng
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Zusammenfassung:Mycophenolate mofetil is made non-catalytically by refluxing mycophenolic acid with 2-morpholinoethanol in an inert organic solvent capable of azeotropic removal of water.