ΠΑΡΑΓΩΓΑ ΜΟΡΦΟΛΙΝΗΣ ΓΙΑ ΧΡΗΣΗ ΩΣ ΑΓΩΝΙΣΤΕΣ ΝΤΟΠΑΜΙΝΗΣ ΣΤΗΝ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ ΣΕΞΟΥΑΛΙΚΗΣ ΔΥΣΛΕΙΤΟΥΡΓΙΑΣ I.Α

Η παρούσα εφεύρεση παρέχει ενώσεις του τύπου (I), (la) και (lb): The present invention provides for compounds of formula (I), (la) and (lb) Wherein: A is selected from C-X and N, B is selected from C-Y and N, R is selected from H and (C1-C6)alkyl R is selected from H and (C1-C6)alkyl, X is selected...

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Hauptverfasser: BAXTER ANDREW DOUGLAS, HEPWORTH DAVID, COOK ANDREW SIMON, WONG STEPHEN KWOK-FUNG, ALLERTON CHARLOTTE MOIRA NORFOR
Format: Patent
Sprache:Greek
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Zusammenfassung:Η παρούσα εφεύρεση παρέχει ενώσεις του τύπου (I), (la) και (lb): The present invention provides for compounds of formula (I), (la) and (lb) Wherein: A is selected from C-X and N, B is selected from C-Y and N, R is selected from H and (C1-C6)alkyl R is selected from H and (C1-C6)alkyl, X is selected from H, HO, C(O)NH2, NH2 Y is selected from H HO,, NH2, Br, Cl and F Z is selected from H, HO, F, CONH2 and CN; And pharmaceutically acceptable salts, solvates and prodrugs thereof; With the provisos that: for a compound of formula (I), (la) or (lb), when A is C-X, B is C-Y, at least one of X, Y and Z must be OH; for a compound of formula (I), when A is C-X and B is C-Y, Y is H, Z is H, R is H and R is H, then X cannot be OH; these compounds are useful as dopamine agonists for the treatment of i.a. secual dysfunction.