COMPOSICIONES VACUNALES OBTENIDAS A PARTIR DE STREPTOMYCES

La presente invención se relaciona con el campo de la inmunología, específicamente con composiciones vacunales a partir de Streptomyces para la prevención de enfermedades infecciosas, tumorales, alérgicas y autoinmunes. Las composiciones vacunales comprenden una o más cepas salvajes del género Streptomyces o cepas mutantes o recombinantes expresando antígenos heterólogos derivados de las mismas, específicamente pueden emplearse cepas vivas de Streptomyces lividans, Sterptomyces coelicolor y Streptomyces Sp. The present invention relates to the filed of immunology and, more specifically, to the control of infectious diseases caused by microbacteria, which is based on the use of vaccines for the prevention of said diseases. The inventive vaccines have been developed with the use of live strains of Streptomyces, which may or may not express antigens of M. tuberculosis, and have demonstrated their protective capacity against the threat of BCG and M. tuberculosis after being administered by different routes. The invention also relates to the use of strains of Streptomyces for the expression of heterologous antigens of vaccinal interest.