ZPUSOB PRIPRAVY KRYSTALCKE FORMY (4,5,6R,8R) METHYL 9 OXO 11 ALFA, 15 ALFA DIHYDROXY 16FENOXY 17,1G,19, 20 TETRANORPROSTA 4,5,13(E) TRIENOATU

This invention relates to a process for making an enantiomer or racemic mixture of a compound of the formula wherein R is hydrogen, lower alkyl or a pharmaceutically acceptable, non-toxic salt of a compound wherein R is hydrogen; X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy, and...

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Hauptverfasser: WREN DUOGLAS L.,US, VAN HORN ALBERT R.,US, COOPER GARY F.,US, LI TSUNG TEE,US, BEARD COLIN CH.,US
Format: Patent
Sprache:eng
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Zusammenfassung:This invention relates to a process for making an enantiomer or racemic mixture of a compound of the formula wherein R is hydrogen, lower alkyl or a pharmaceutically acceptable, non-toxic salt of a compound wherein R is hydrogen; X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy, and the wavy lines represent the alpha or beta configuration with the proviso that when one wavy line is a alpha the other is beta ; novel intermediates useful for preparing these compounds; and processes for making the intermediates.