PROCESS FOR PREPARING A-21978C ANTIBIOTIC IN THE FORM OF A COMPLEX OR ITS FACTORS

An improved process is provided for producing A-21978C cyclic peptide derivatives having a C2-C14 alkonoyl side chain which comprises feeding a C2-C14 alkanoic acid, or an ester or salt thereof, to the A-21978C-producing culture during the production stages of the fermentation. In addition, a new pr...

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Hauptverfasser: TIETZ ANTHONY J, ZMIJEWSKI MILTON J, HUBER MARY LOUISE B, EATON TOM E, PIEPER RICHARD L, FORD LYNDA M, HUBER FLOYD M, GOFREY OTIS W. JR
Format: Patent
Sprache:eng
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Zusammenfassung:An improved process is provided for producing A-21978C cyclic peptide derivatives having a C2-C14 alkonoyl side chain which comprises feeding a C2-C14 alkanoic acid, or an ester or salt thereof, to the A-21978C-producing culture during the production stages of the fermentation. In addition, a new process is provided for producing the A-21978C antibiotics which comprises cultivating under aerobic conditions a new strain of microorganism.