2-SUBSTITUTED QUINOLINES, PROCESS OF THEIR PREPARATION AND THEIR USE INMEDICAMENTS
2-substituted quinolines of the general formula The title compounds are prepared by reacting either the corresponding halomethylquinolines with substituted phenols, then optionally alkylating these and hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivative...
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creator | MATZKE MICHAEL DR HATZELMANN ARMIN DR MULLER-PEDDINGHAUS REINER DR RADDATZ SIEGFRIED DR THEISEN-POPP PIA DR MOHRS KLAUS-HELMUT DR KOHLSDORFER CHRISTIAN DR FRUCHTMANN ROMANIS |
description | 2-substituted quinolines of the general formula The title compounds are prepared by reacting either the corresponding halomethylquinolines with substituted phenols, then optionally alkylating these and hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivatives with sulphonamides. The novel phenyl-substituted quinolines can be used as active compounds in medicaments, in particular as lipoxygenase inhibitors. |
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The novel phenyl-substituted quinolines can be used as active compounds in medicaments, in particular as lipoxygenase inhibitors.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 2-SUBSTITUTED QUINOLINES, PROCESS OF THEIR PREPARATION AND THEIR USE INMEDICAMENTS |
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