PROCESS FOR PREPARING DERIVATIVES OF 2-BROM-ALPHA-ERGO-CRYPTINE

The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.

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Bibliographische Detailangaben
Hauptverfasser: GAZDAG MARIA DR.,HU, MEGYERI GABOR ,HU, TRISCHLER FERENC DR.,CS, BOGSCH ERIK ,HU, KASSAI ANNA,HU, SZEPESI GABOR ,HU, STEFKO BELA DR.,HU, KOVACS LAJOS ,HU, KEVE TIBOR DR.,HU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.