ZPUSOB VYROBY 1,8-DIHYDROXY-10-ACYL-9-ANTHRONU

The invention relates to a method for the preparation of 1,8-dihydroxy-10-acyl-9-anthrones, especially for use in the treatment of psoriasis, having the formula: where R is an alkyl group having 2-4 carbon atoms, by using as the initial material, 1,8-dihydroxy-9-anthrone and an acid chloride having...

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Hauptverfasser: HONKANEN ERKKI J.,FI, PIPPURI AINO K.,FI, KAIRISALO PEKKA J.,FI
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to a method for the preparation of 1,8-dihydroxy-10-acyl-9-anthrones, especially for use in the treatment of psoriasis, having the formula: where R is an alkyl group having 2-4 carbon atoms, by using as the initial material, 1,8-dihydroxy-9-anthrone and an acid chloride having the formula RCOC2, where R represents the same as above. In accordance with the invention, harmful benzene is replaced with, for example toluene; this replacing is possible because pyridine is replaced with 2,6-dimethyl pyridine.