PROCESS FOR PREPARING 2-SUBSTITUTED 1,3-PROPYLIDENDIPHOSPHONATES
2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R1 and R2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases. They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-prop...
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| creator | PHAN HIEU T.,CH BENTZEN GRAIG L. CHAVANNES-DE-BOGIS,CH ROSSIER JEAN-ROBERT,CH KALATHAKIS KYRIACOS,CH NQUYEN MONG L.,CH GUYON-GELLIN V.,FR NIESOR ERIC,CH |
| description | 2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R1 and R2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases. They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-propanediols substituted in position 2. (I) . |
| format | Patent |
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CHAVANNES-DE-BOGIS,CH</au><au>ROSSIER JEAN-ROBERT,CH</au><au>KALATHAKIS KYRIACOS,CH</au><au>NQUYEN MONG L.,CH</au><au>GUYON-GELLIN V.,FR</au><au>NIESOR ERIC,CH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING 2-SUBSTITUTED 1,3-PROPYLIDENDIPHOSPHONATES</title><date>1989-03-14</date><risdate>1989</risdate><abstract>2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R1 and R2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases. They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-propanediols substituted in position 2. (I) .</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PREPARING 2-SUBSTITUTED 1,3-PROPYLIDENDIPHOSPHONATES |
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