ALKYLAMIDES OF CARBOXYALKANOYLPEPTIDES

A method is described for the preparation of novel alkylamides of carboxyalkanoyl peptides of the formula wherein R is an aralky or an alkyl group of 1-5 carbon atoms, A is a residue of peptidically bound proline or alanine, B is a straight bond or a residue of peptidically bound proline or alanine...

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Hauptverfasser: SLABY JAN MUDR.,CS, KASAFIREK EVZEN CSC.,CS, ROUBALOVA ALENA,CS, FRIC PREMYSL DOC.MUDR.DRSC.,CS
Format: Patent
Sprache:eng
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Zusammenfassung:A method is described for the preparation of novel alkylamides of carboxyalkanoyl peptides of the formula wherein R is an aralky or an alkyl group of 1-5 carbon atoms, A is a residue of peptidically bound proline or alanine, B is a straight bond or a residue of peptidically bound proline or alanine and X is a CH=CH group or a methylene group of 1-3 carbon atoms. The described compounds are capable of inhibiting elastase.