PROCESS FOR PREPARING THIAZOLYL COMPOUNDS

PROCESS FOR PREPARING THIAZOLYL COMPOUNDS

Improvements introduced in the object of the main patent no. 423,056, filed on February 8, 1974, by PROCEDURE FOR THE PRODUCTION OF SULFOXIDES, in particular to prepare sulfoxides of formula: **(See formula)** wherein Het and Het'are chosen from imidazole optionally substituted by methyl or bro...

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Bibliographische Detailangaben
Hauptverfasser: HESSELBO,TORBEN,GB, GANELLIN,CHARON R.,GB, WHITE,GEORGE R.,GB, DURANT,GRAHAM J.,GB
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Improvements introduced in the object of the main patent no. 423,056, filed on February 8, 1974, by PROCEDURE FOR THE PRODUCTION OF SULFOXIDES, in particular to prepare sulfoxides of formula: **(See formula)** wherein Het and Het'are chosen from imidazole optionally substituted by methyl or bromine, pyridine optionally substituted by methoxy, hydroxy, chlorine or bromine, thiazole and isothiazole; Z is sulfur, SO or methylene and X is sulfur, CHNO2 or NCN characterized in that it comprises treating a compound of the formula: Het-CH2S (CH2) NHQ wherein Q is hydrogen or, when X is CHNO2 or NCN, -CXeNH (CH2) 2ZCH2-Het', with a suitable oxidizing agent. (Machine-translation by Google Translate, not legally binding)