METHOD OF PREPARING IMIDAZOLYL COMPOUNDS
Procedure to prepare anti-histamine compounds, of formula: **(See formula)** where n is 2 or 3; 2 is sulfur or methylene; X ex sulfur, CHNO2 or NCH; Y is hydrogen, lower alkyl, or Het CH2Z'(CH2) n', where Het is 5-Mdroxymethyl-4-imidazolyl or is an imidazole ring optionally substituted by...
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| creator | WHITE,GEORGE R.,GB |
| description | Procedure to prepare anti-histamine compounds, of formula: **(See formula)** where n is 2 or 3; 2 is sulfur or methylene; X ex sulfur, CHNO2 or NCH; Y is hydrogen, lower alkyl, or Het CH2Z'(CH2) n', where Het is 5-Mdroxymethyl-4-imidazolyl or is an imidazole ring optionally substituted by methyl or bromine, a pyridine ring optionally substituted by hydroxy, methoxy, chlorine or bromine, a thiazolyl ring, or an isothiazolyl ring; Z'is sulfur or methylene; and n'is 2 or 3, characterized in that it comprises reacting a compound of formula: **(See formula)** where X is NCN or CHNO2, Q is lower alkyl, B is SQ', OQ', where Q'is lower alkyl, or NHY, where Y is defined as above, and A is sulfur, oxygen or when X is CHNO2 and B is SQ', SO, with a compound of the formula: **(See formula)** where Z is sulfur or methylene and n is 2 or 3. (Machine-translation by Google Translate, not legally binding) |
| format | Patent |
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(Machine-translation by Google Translate, not legally binding)</abstract><edition>3</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD OF PREPARING IMIDAZOLYL COMPOUNDS |
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