METHOD OF PREPARING SULPHIDES

Sulfides of the general formula WHEREIN R1 is H or alkyl, R2 is =O, (H,OH), or (H,lower-acyloxy), R3 is H, OH or lower-acyloxy, R4 is alkyl or alkyl substituted by F, OH, lower-acyloxy, phenyl or p-tolyl, and A is alkylene which can be mono- or polysubstituted by F, and the physiologically acceptabl...

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Hauptverfasser: KRAEMER,JOSEF,DE, RADUNZ,HANS,DE, BAUMGARTH,MANFRED,DE, ORTH,DIETER,DE, HARTING,JUERGEN,DE
Format: Patent
Sprache:eng
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Zusammenfassung:Sulfides of the general formula WHEREIN R1 is H or alkyl, R2 is =O, (H,OH), or (H,lower-acyloxy), R3 is H, OH or lower-acyloxy, R4 is alkyl or alkyl substituted by F, OH, lower-acyloxy, phenyl or p-tolyl, and A is alkylene which can be mono- or polysubstituted by F, and the physiologically acceptable salts thereof, possess, in addition to a blood-pressure-lowering activity, prostaglandin-type and antiprostaglandin-type effects.