METHOD OF PRODUCING NEW CHROMOGEN ENZYME SUBSTRATE

Method for the quantitative determination of serine proteases which includes contacting the substance for which the determination is desired with a diagnostically active chromogenic substrate with good stability and high specificity to serine proteases having the formula: H-D-A1-A2-A3-NH-R or salts...

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Hauptverfasser: AURELL,LEIF E.,SE, CLAESON,KARL G.,SE, GUSTAVSSON,STIG I.,SE, CLAUSSON,GUN A.,SE, AF EKENSTAM,BO THURESSONAF,SE, KARLSSON,BIRGITTA G.,SE
Format: Patent
Sprache:eng
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Zusammenfassung:Method for the quantitative determination of serine proteases which includes contacting the substance for which the determination is desired with a diagnostically active chromogenic substrate with good stability and high specificity to serine proteases having the formula: H-D-A1-A2-A3-NH-R or salts thereof, wherein A1 is Gly, Ala, Val, Leu, Ile, Pip, Pro, or Aze; A2 is Gly, Ala, Val, Leu, Ile, Pip, Pro, Aze, or Phe; A3 is Arg, Lys, or Orn, and R is a chromophoric group.