RECOMBINANTLY PREPARED BLOOD FACTORS, METHOD OF STATED BLOOD FACTORS EXPRESSION AND ALSO RECOMBINANTS OF VIRUS OF VACCINE THAT IS USED IN STATED PROCESS

Recombinantly produced blood factors as well as a process for their preparation are described, said blood factors having a ratio of biologically active form to antigenic form of at least 50 %, preferably in the range of 60 to 90 %. There are also disclosed recombinant vaccinia viruses used in the ab...

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Hauptverfasser: SCHEIFLINGER FRIEDRICH ,AT, MACGILLIVRAY ROSS T.A.,CA, BODEMER WALTER DR.,AT, EIBL JOHANN DR.,AT, DORNER FRIEDRICH ,AT, FALKNER FALKO-GUNTER DR.,AT
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Sprache:eng
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Zusammenfassung:Recombinantly produced blood factors as well as a process for their preparation are described, said blood factors having a ratio of biologically active form to antigenic form of at least 50 %, preferably in the range of 60 to 90 %. There are also disclosed recombinant vaccinia viruses used in the above process. The process according to the invention provides an improved expression system with high post-translational capacity under stable expression conditions.