KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers. En la presente, se proveen inhibidores de KRAS G12C, composiciones de estos y métodos...

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Bibliographische Detailangaben
Hauptverfasser: SHIN, Youngsook, CEE, Victor J, ALLEN, Jennifer Rebecca, NGUYEN, Thomas T, LANMAN, Brian Alan, LOPEZ, Patricia, BOOKER, Shon, ALLEN, John Gordon, WURZ, Ryan Paul, KOPECKY, David John, CHEN, Jian, LIU, Longbin, REED, Anthony B, NISHIMURA, Nobuko, TAMAYO, Nuria A
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers. En la presente, se proveen inhibidores de KRAS G12C, composiciones de estos y métodos para su uso. Dichos inhibidores son útiles para el tratamiento de múltiples trastornos, los que incluyen cáncer pancreático, colorrectal y pulmonar.