ANTIBODIES BINDING TO CD3 AND CD19

ANTIBODIES BINDING TO CD3 AND CD19

The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods f...

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Bibliographische Detailangaben
Hauptverfasser: FREIMOSER-GRUNDSCHOBER, Anne, HOSSE, Ralf, GONZALEZ NICOLINI, Maria, Valeria, KNAUPP, Alexander, KLEIN, Christian, TROCHANOWSKA, Halina, UMAÑA, Pablo, MOESSNER, Ekkehard, RICHTER, Wolfgang, WALDHAUER, Inja
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease. La presente invención se refiere en general a anticuerpos que se unen a CD3 y CD19, por ejemplo, para activar linfocitos T. Además, la presente invención se refiere a polinucleótidos que codifican dichos anticuerpos, y vectores y células huésped que comprenden dichos polinucleótidos. La invención se refiere además a procedimientos para producir los anticuerpos y a procedimientos para usarlos en el tratamiento de una enfermedad.