BICYCLIC AMINES AS CDK2 INHIBITORS

The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same La presente solicitud proporciona aminas bicíclicas que inhiben la cinasa dependiente de ciclina 2 (...

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Bibliographische Detailangaben
Hauptverfasser:	WINTERTON, Sarah, XIAO, Kaijiong, LI, Zhenwu, HUMMEL, Joshua, YE, Min, XU, Meizhong, LO, Yvonne, CHEN, Yingnan, YAO, Wenqing, FAVATA, Margaret, WU, Liangxing, YE, Yingda, QIAN, Ding-Quan
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same La presente solicitud proporciona aminas bicíclicas que inhiben la cinasa dependiente de ciclina 2 (CDK2), así como composiciones farmacéuticas de estas, y métodos de tratamiento del cáncer mediante su uso.