DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR

Described herein are compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are defined herein, their use as diacylglycerol acyltransferase 2 (DGAT2) inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, NASH. En la...

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Bibliographische Detailangaben
Hauptverfasser:	FILIPSKI, Kevin James, GARNSEY, Michelle Renee, EDMONDS, David James, LEE, Jack Chang Hung, FUTATSUGI, Kentaro, SMALTZ, Daniel Jonathan
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described herein are compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are defined herein, their use as diacylglycerol acyltransferase 2 (DGAT2) inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, NASH. En la presente se describen compuestos de la Formula (I)