CD73 INHIBITORS

The present invention provides 5-[5]-[2-cycloa Ikyl ]-6-pyridazin-3-yl ]- IH-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer. (Formula (I)) La presente invención proporciona 5-[5]-[2-cicloalquil]-6-piri...

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Bibliographische Detailangaben
Hauptverfasser:	WANG, Yan, ZHAO, Genshi, HOWELL, Jennifer Marie, DALLY, Robert Dean, HEINZ, Lawrence Joseph II, NJOROGE, Frank George, GARCIA PAREDES, Maria Cristina
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides 5-[5]-[2-cycloa Ikyl ]-6-pyridazin-3-yl ]- IH-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer. (Formula (I)) La presente invención proporciona 5-[5]-[2-cicloalquil]-6-piridazin-3-il]-1Hpirimidin-2,4-diona, o sales aceptables desde el punto de vista farmacéutico de este, que inhiben la actividad de CD73 y son útiles en el tratamiento contra el cáncer.