GRANULACION EN HUMEDO UTILIZANDO UN AGENTE SECUESTRANTE DE AGUA
Se describen tabletas que comprenden formulaciones estables hidroliticamente de sal disodica de (6-(5-fluor-2-(2,4-5trimetoxifenilamino) pirimidin-4-ilamino)-2,2-dimetil-3-oxo-2h-pirido. Disclosed are tablets comprising hydrolytically stable formulations of (6-(5-fluoro-2-(3,4,5-trimethoxyphenylamin...
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Format: | Patent |
Sprache: | spa |
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Zusammenfassung: | Se describen tabletas que comprenden formulaciones estables hidroliticamente de sal disodica de (6-(5-fluor-2-(2,4-5trimetoxifenilamino) pirimidin-4-ilamino)-2,2-dimetil-3-oxo-2h-pirido.
Disclosed are tablets comprising hydrolytically stable formulations of (6-(5-fluoro-2-(3,4,5-trimethoxyphenylamino)pyrimidin-4-ylamino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl phosphate disodium salt (Compound 1) prepared by a wet granulation process. |
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