FORMAS CRISTALINAS GLYT1

La presente invencion se refiere a cuatro formas cristalinas distintas y a una forma amorfa de la [4-(3-fluor-5-trifluormetil-piridin-2-il)-piperazin-1-il] - [5-metanosulfonil-2-( (S) -2,2,2,-trifluor-1-metil-etoxi) -fenil] -metanona y a su utilizacion para la fabricacion de composiciones farmaceuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DEYNET-VUCENOVIC, ANNETTE, PINARD EMMANUEL, BUBENDORF, ANDRE, GRASSMANN, OLAF, SCHWITTER, URS, LINDENSTRUTH, KAI, ROHRER, FRANZISKA E, DIODONE, RALPH
Format:	Patent
Sprache:	spa
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	La presente invencion se refiere a cuatro formas cristalinas distintas y a una forma amorfa de la [4-(3-fluor-5-trifluormetil-piridin-2-il)-piperazin-1-il] - [5-metanosulfonil-2-( (S) -2,2,2,-trifluor-1-metil-etoxi) -fenil] -metanona y a su utilizacion para la fabricacion de composiciones farmaceuticas. The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.