Inhibidores de la péptido desformilasa

The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide compounds of Formula (I): or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MCKEOWN ROBERT RAHN, GILLIAN JASON MICHAEL, WILLIAMS GLENN R, AUBART KELLY M, QIN DONGHUI
Format: Patent
Sprache:spa
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Beschreibung
Zusammenfassung:The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide compounds of Formula (I): or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity and in treatment methods for bacterial infections.