NOVEL CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

NOVEL CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The invention relates to novel 7 beta -[2-(2-aminothiazol-4-yl)-(Z)-2-alkoxyimino-acetamido]-3-[(2-mercapto- 1,3,4-th iadiazol-5-yl)thiomethyl]-ceph-3-em-4-carboxylic acids of the formula wherein R represents a C1-4 alkyl group, and pharmaceutically acceptable salts and esters thereof. The antibacte...

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Bibliographische Detailangaben
Hauptverfasser: SANDOR ELEK, ILDIKO MIHOK NE'E BORBE'LY, AGNES PREKOPA NEE CSERNYANSZKY, ISTVAN KOCZKA, MIKLOS MIHOK, KATALIN MAROSSY, SANDOR JANCSO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The invention relates to novel 7 beta -[2-(2-aminothiazol-4-yl)-(Z)-2-alkoxyimino-acetamido]-3-[(2-mercapto- 1,3,4-th iadiazol-5-yl)thiomethyl]-ceph-3-em-4-carboxylic acids of the formula wherein R represents a C1-4 alkyl group, and pharmaceutically acceptable salts and esters thereof. The antibacterial compounds of the invention can be prepared by methods well known in the cephalosporin chemistry.