Elastic bubble interception ring in perfusion pipeline suitable for cell perfusion culture

The utility model discloses an elastic bubble interception ring in a perfusion pipeline, which is suitable for cell perfusion culture. The elastic bubble interception ring consists of a support frame and a flexible pipeline, in the initial stage of perfusion culture, bubbles in the pipeline can be d...

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Bibliographische Detailangaben
Hauptverfasser: SHENG LEI, BAI ZHONGHU, NIE JIANQI, SUN YANG, LIU JUNKAI
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The utility model discloses an elastic bubble interception ring in a perfusion pipeline, which is suitable for cell perfusion culture. The elastic bubble interception ring consists of a support frame and a flexible pipeline, in the initial stage of perfusion culture, bubbles in the pipeline can be discharged into the reactor through the extension of the elastic bubble interception ring and the conversion of the flowing direction of liquid; then the elastic bubble interception ring is bent into a coil shape through the supporting frame, bubbles (gas) in a perfusion pipeline can be intercepted in the perfusion culture process, the bubbles (gas) are prevented from entering the hollow fiber membrane column or the fluid driving unit, and therefore efficient and stable operation of perfusion culture is achieved. 本实用新型公开了一种适用于细胞灌流培养的灌流管路中弹性气泡截留环,弹性气泡截留环由支撑架与柔性管路组成。在灌流培养初期,通过弹性气泡截留环的伸展并配合液体流动方向的转换,可将管路中的气泡排出到反应器内;随后通过支撑架将弹性气泡截留环弯曲成线圈状,在灌流培养过程中可实现对灌流管路气泡(气体)的截留,防止气泡(气体)进入到中空纤维膜柱或流体驱动单元,从而实现灌流培养的高效稳定运行。