Detachable fixed bed bioreactor suitable for virus vector production

The utility model discloses a detachable fixed bed bioreactor suitable for virus vector production, which comprises a tank body, a culture bin, a stirring bin, a fixed bed mechanism and a sampling strip, the culture bin is arranged in the tank body, and the fixed bed mechanism is arranged in a cultu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WEI BO, TAN HU, WANG JIANGKAI
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The utility model discloses a detachable fixed bed bioreactor suitable for virus vector production, which comprises a tank body, a culture bin, a stirring bin, a fixed bed mechanism and a sampling strip, the culture bin is arranged in the tank body, and the fixed bed mechanism is arranged in a culture bin accommodating part of the culture bin; the bottom of the culture bin is connected with the stirring bin, a spoiler is arranged between the culture bin and the stirring bin, and the spoiler is installed at the top of the stirring bin. When cell inoculation is carried out at the initial stage, thick cell suspension cannot be blocked at the bottom of the fixed bed, and cells can be uniformly distributed; in the cell growth process, culture medium liquid flow penetrates through the surface of the fixed bed mechanism at a constant speed and can make full contact with cells without dead corners, nutrient substances needed by the cells are more balanced, and the cell growth state is more uniform; the culture bin an