Drug carrier sphere particle structure

The utility model provides a drug carrier spherical particle structure which comprises a PLGA (poly (lactic-co-glycolic acid)) shell, and a modified amino coating is arranged outside the PLGA shell; an accommodating space is formed in the PLGA shell, a plurality of magnetic beads are arranged in the...

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Bibliographische Detailangaben
Hauptverfasser: JIANG LIJUN, ZHANG LINXIANG, YAN JIJIE, LI YULIN, LIU TIELONG, LIAN RUIXIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The utility model provides a drug carrier spherical particle structure which comprises a PLGA (poly (lactic-co-glycolic acid)) shell, and a modified amino coating is arranged outside the PLGA shell; an accommodating space is formed in the PLGA shell, a plurality of magnetic beads are arranged in the accommodating space, and one or more bulges are arranged on the outer surfaces of the magnetic beads; according to the drug carrier spherical particle structure, the modified amino coating is additionally arranged outside the PLGA shell, and the magnetic beads with the protrusions are additionally arranged inside the PLGA shell, so that the drug can be released in time after the drug carrier spherical particle structure is injected; the drug carrier sphere particle structure is not prone to accumulation and blockage when moving in cerebrospinal fluid, the treatment effect is improved, the structure is simple and reasonable, and operation is convenient. 本实用新型提供了一种药物载体球颗粒结构,包括PLGA外壳,所述PLGA外壳的外部具有修饰氨基涂层;所述PLGA外壳的内部具有