Chromatography cooling column

The utility model discloses a chromatography cooling column, and belongs to the field of protein separating and purifying machinery equipment. The chromatography cooling column comprises a column body, a column cover is arranged on the column body, a column base plate is connected below the column body, the column body is divided to be two layers, wherein the inner layer is of a chromatography column, a sandwich layer covers the chromatography column, a cooling water inlet is formed below the sandwich layer, a cooling water outlet is formed on the top of the sandwich layer, and a temperature sensor is arranged outside the sandwich layer. Through additionally arranging the sandwich layer on the chromatography column, during a separating and purifying process of protein, the cooling water enters the chromatography column sandwich layer through a closed pipeline to circulate to cool, therefore the temperatures of the solution in the chromatography column and the medium are reduced greatly; meanwhile, as the temperature sensor is arranged outside the sandwich layer, the requirements of protein on temperature in the chromatography column during the separating and purifying process can be met at any time.