Methods of treating type I diabetes by blocking VEGF-mediated activity

Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as the VEGF fusion protein trap of SEQ ID NO: 2 capable of binding and blocking VEGF. The method of the invention...

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1. Verfasser: CAO JINGTAI,WANG LI-HSIEN,LIN HSIN C.,SLEEMAN MARK W.,WIEGAND STANLEY J
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creator CAO JINGTAI,WANG LI-HSIEN,LIN HSIN C.,SLEEMAN MARK W.,WIEGAND STANLEY J
description Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as the VEGF fusion protein trap of SEQ ID NO: 2 capable of binding and blocking VEGF. The method of the invention may be combined with other therapies, such as with insulin therapy.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Methods of treating type I diabetes by blocking VEGF-mediated activity
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