Methods of treating type I diabetes by blocking VEGF-mediated activity

Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as the VEGF fusion protein trap of SEQ ID NO: 2 capable of binding and blocking VEGF. The method of the invention...

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Bibliographische Detailangaben
1. Verfasser:	CAO JINGTAI,WANG LI-HSIEN,LIN HSIN C.,SLEEMAN MARK W.,WIEGAND STANLEY J
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as the VEGF fusion protein trap of SEQ ID NO: 2 capable of binding and blocking VEGF. The method of the invention may be combined with other therapies, such as with insulin therapy.