Image data processing system for compartmental analysis

The invention relates to a data processing system (1) for the evaluation of image data, particularly of PET-images (I), that represent the time varying concentration of a tracer substance like F-MISO in an object (20). The data processing system (1) comprises a library module (48) with analytical so...

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Bibliographische Detailangaben
1. Verfasser:	PAULUS TIMO,PELIGRAD DRAGOS-NICOLAE,SPIES LOTHAR
Format:	Patent
Sprache:	eng
Schlagworte:	CALCULATING COMPUTING COUNTING HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA IMAGE DATA PROCESSING OR GENERATION, IN GENERAL INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS PHYSICS
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Beschreibung
Zusammenfassung:	The invention relates to a data processing system (1) for the evaluation of image data, particularly of PET-images (I), that represent the time varying concentration of a tracer substance like F-MISO in an object (20). The data processing system (1) comprises a library module (48) with analytical solutions (C,(t)) for several compartment models. Preferably the library also contains the analytical gradients with respect to the parameters of interest. From the library an appropriate solution for each study can be chosen by a user. The use of analytical functions together with the information about the error (6A(t)) of the input data (either via noise models 43 or via a simulation 44) allows to extract all parameters mandatory to fully understand the kinetics of complex models (more than one tissue compartment) on a per-voxel basis in a robust way in real-time.