Butyrylcholinesterase selective inhibitors
The invention provides butyrylcholinesterase inhibitors of Formula I which contain an heterocyclic moiety and a 4 piperidine moiety with a linker in between. The compounds show a very high activity and selectivity towards BuChE, making them useful for the treatment and or prophylaxis or cognitive di...
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| creator | MARTINEZ GIL ANA,RUBIO ARRIETA LAURA,MUNOZ RUIZ PILAR,DORRONSORO DIAZ ISABEL,GARCIA PALOMERO ESTHER,DEL MONTE MILLAN MARIA,MEDINA PADILLA MIGUEL |
| description | The invention provides butyrylcholinesterase inhibitors of Formula I which contain an heterocyclic moiety and a 4 piperidine moiety with a linker in between. The compounds show a very high activity and selectivity towards BuChE, making them useful for the treatment and or prophylaxis or cognitive disorders and/or neurodegenerative disorders. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Butyrylcholinesterase selective inhibitors |
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