Antibodies to MAdCAM

Antibodies to MAdCAM

A human monoclonal antibody or its antigen-binding portion that specifically binds to Mucosal Adressin Cell Adhesion Molecule (MAdCAM), is new. A human monoclonal antibody or its antigen-binding portion, produced by a hybridoma cell line, that specifically binds to Mucosal Adressin Cell Adhesion Mol...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KELLERMANN SIRID-AIMEE, PULLEN NICHOLAS, HAAK-FRENDSCHO MARY, GREEN LARRY L, MOLLOY ELIZABETH
Format: Patent
Sprache:chi ; eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A human monoclonal antibody or its antigen-binding portion that specifically binds to Mucosal Adressin Cell Adhesion Molecule (MAdCAM), is new. A human monoclonal antibody or its antigen-binding portion, produced by a hybridoma cell line, that specifically binds to Mucosal Adressin Cell Adhesion Molecule (MAdCAM), where the antibody is selected from an antibody comprising any of the 17 sequences of 233-241 amino acids (SEQ ID NOS: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, 54, 58, 62, 66 or 68), without the signal sequences, where the heavy chain of the antibody or its portion comprises the heavy chain CDR1, CDR2 and CDR3 amino acid sequences of a reference monoclonal antibody and/or where the light chain comprises the light chain CDR1, CDR2 and CDR3 amino acid sequences of a reference monoclonal antibody, where the antibody or its portion comprises one or more of an FR1, FR2, FR3 or FR4 amino acid sequence of a human monoclonal antibody, where the reference or human monoclonal antibody is selected from 1.