Indene derivatives and process for the preparation thereof

Indene derivatives and process for the preparation thereof

The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus,they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syn...

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Hauptverfasser: AHN JIN HEE, CHEON HYAE GYEONG, YANG SUNG-DON, YOO SUNG-EUN, MO KIL WOONG, KIM SUN MEE, KANG SEUNG KYU, LEE JEONG-HYUNG, KIM SUNG SOO, KIM KWANG-ROK, LEE JAE MOK, RHEE SANG DAL, KIM SEUNG JUN, LEE KOUN HO, KIM NAM GEE, JUNG WON HOON, KANG HYE JUNG, KIM JONG HOON, PARKSUNG DAE
Format: Patent
Sprache:chi ; eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus,they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.