Inhibitors of serine proteases, particularly HCV NS3-HS4A protease

The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus...

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Bibliographische Detailangaben
1. Verfasser: COTTRELL KEVIN M.,COURT JOHN J.,DEININGER DAVID D.,FARMER LUC J.,PITLIK JANOS,PERNI ROBERT B
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.