Pharmaceutical composition for thrombin peptide derivatives

Disclosed are pharmaceutical compositions comprising a thrombin peptide derivatives and a chelating agent and/or a pharmaceutically acceptable thiol-containing compound. The pharmaceutical compositions optionally further comprise an antioxidant. Also, disclosed are methods for activating the non-pro...

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Bibliographische Detailangaben
1. Verfasser: HOBSON DAVID W.,CROWTHER ROGER S.,CARNEY DARRELL H.,TANG ANDREW P. K
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed are pharmaceutical compositions comprising a thrombin peptide derivatives and a chelating agent and/or a pharmaceutically acceptable thiol-containing compound. The pharmaceutical compositions optionally further comprise an antioxidant. Also, disclosed are methods for activating the non-proteolytically activated thrombin receptor in a subject in need of such treatment. The methods comprise the step of administering an effective amount of a thrombin peptide derivative in the pharmaceutical composition described above.