N-acylsulfonamide apoptosis promoters

Disclosed are N-acylsulfonamide compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression of one or more than one anti-apoptotic protein...

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1. Verfasser: BRUNCKO MILAN,DING HONG,ELMORE STEVEN,KUNZER AARON,LYNCH CHRISTOPHER L.,MCCLELLAN WILLIAM,PARK CHEOL-MIN,PETROS ANDREW,SONG XIAOHONG,WANG XILU,TU NOAH,WENDT MICHAEL
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Sprache:eng
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Zusammenfassung:Disclosed are N-acylsulfonamide compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression of one or more than one anti-apoptotic protein family member.