scFvC6.5-TNF-alpha fusion gene and protein, and its preparation

The invention discloses a scFvC6.5- TNF-alpha fusion gene and protein and preparing method with base sequence as sequence graph 1, which is characterized by the following: the scFvC6.5- TNF-alpha fusion gene can produce scFvC6.5- TNF-alpha immune toxin through expressing, degenerating, restoring and...

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Bibliographische Detailangaben
1. Verfasser:	WENFANG,JIANG WU
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a scFvC6.5- TNF-alpha fusion gene and protein and preparing method with base sequence as sequence graph 1, which is characterized by the following: the scFvC6.5- TNF-alpha fusion gene can produce scFvC6.5- TNF-alpha immune toxin through expressing, degenerating, restoring and purifying, which possesses high lethality for HER2/neu tumor cell specifically without killing HER2/neu negative cell. The immune toxin provides potential applying prospect to treat HER2/neu tumor cell.