Secure and efficacious therapy delivery for an extra-systolic stimulation pacing engine

An extra-systolic stimulation (ESS) therapy addresses cardiac dysfunction including heart failure. ESS therapy employs atrial and/or ventricular extra-systoles via pacing-level stimulation to a heart. These extra-systoles must be timed correctly to achieve beneficial effects on myocardial mechanics...

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1. Verfasser: KLECKNER KAREN J.,PRIEVE KATHLEEN A.,GILLBERG JEFFREY M.,ZHOU REBN,ANDERSON KENNETH M.,DENO D. CURTIS,ZILLMER GLENN C.,KLEPFER RUTH N.,SPLETT VINCENTE
Format: Patent
Sprache:eng
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Zusammenfassung:An extra-systolic stimulation (ESS) therapy addresses cardiac dysfunction including heart failure. ESS therapy employs atrial and/or ventricular extra-systoles via pacing-level stimulation to a heart. These extra-systoles must be timed correctly to achieve beneficial effects on myocardial mechanics (efficacy) while maintaining an extremely low level of risk of arrhythmia induction and excellent ICD-like arrhythmia sensing and detection (security). The present invention relates to therapy delivery guidance and options for improved ESS therapy delivery. These methods may be employed individually or in combinations in an external or implantable ESS therapy delivery device.