Quinoline and quinazoline derivatives having affinity for 5HT1-type receptors

Quinoline and quinazoline derivatives having affinity for 5HT1-type receptors

Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided: wherein R1, m, X, R2, n, W, p, Y, Z, R3, R4, R5 and q have the meanings as defined in the description. Methods of preparation and uses thereof in therapy, particularly for CNS disorders such as depression or anxiety...

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Bibliographische Detailangaben
1. Verfasser: BERGAUER MARKUS,BERTANI BARBARA,BIAGETTI MATTEO,BROMIDGE STEVEN MARK,FALCHI ALESSANDRO,LESLIE COLINPHILIP,MERLO GIANCARLO,PIZZI DOMENICA ANTONIA,RINALDI MARILISA,STASI LUIGI PIERO,TIBASCO JESSICA,VON
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided: wherein R1, m, X, R2, n, W, p, Y, Z, R3, R4, R5 and q have the meanings as defined in the description. Methods of preparation and uses thereof in therapy, particularly for CNS disorders such as depression or anxiety, are also disclosed.