Piperazine derivatives for the treatment of HIV infections

Piperazine derivatives for the treatment of HIV infections

This invention relates to a compound of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, wherein R to R are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation, compositions containing them and the uses o...

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Bibliographische Detailangaben
1. Verfasser: MIDDLETON DONALD STUART,MOWBRAY CHARLES ERIC,STEPHENSON PETER THOMAS,WILLIAMS DAVID HOWARD
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:This invention relates to a compound of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, wherein R to R are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation, compositions containing them and the uses of such derivatives. The compounds of the present invention inhibit the interaction of gp 120 with CD4 and are therefore of use in the treatment of HIV, a retroviral infection genetically related to HIV, or AIDS.