Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases

The present invention provides compounds, and pharmaceutical compositions containing those compounds, that are active at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.

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Bibliographische Detailangaben
1. Verfasser:	VAN WAGENEN BRADFORD C,MOE SCOTT T.,SMITH DARYL L.,SHEEHAN SUSAN M.,SCHERBAKOVA IRINA,TRAVATO RICHARD,WALTON RUTH,BARMORE ROBERT,DELMAR ERIC G.,STORMANN THOMAS M
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds, and pharmaceutical compositions containing those compounds, that are active at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.